They prefer a moderately fertile, moist but well-drained soil, slightly acid and a place in a sheltered, sunny position. Plant in late autumn to winter, 8-10 m apart if you live in a warm area, and if you live in a cold area plant in spring. In frost-prone areas grow tender species in a temperate greenhouse. Mulberries have brittle roots, so they need to be handled with care when planting them out. They should only be pruned when fully dormant, in winter, because mulberries bleed profusely if cut or damaged between early spring and summer. Ideally prune only badly placed branches and dead wood. If bleeding does occur, cauterize the wounds as quickly as possible with a hot poker or other iron implement.
Mulberries may be propagated hardwood cuttings of about 18 cm long, taken with a heel in autumn, in a prepared bed in ca cold frame. You can also root semi-ripe cuttings in summer. You can try to propagate mulberries from seeds sown in containers outdoors during autumn.